The life of plant mitochondrial complex I

verfasst von

Hans Peter Braun, Stefan Binder, Axel Brennicke, Holger Eubel, Alisdair R. Fernie, Iris Finkemeier, Jennifer Klodmann, Ann Christine König, Kristina Kühn, Etienne Meyer, Toshihiro Obata, Markus Schwarzländer, Mizuki Takenaka, Anja Zehrmann

Abstract

The mitochondrial NADH dehydrogenase complex (complex I) of the respiratory chain has several remarkable features in plants: (i) particularly many of its subunits are encoded by the mitochondrial genome, (ii) its mitochondrial transcripts undergo extensive maturation processes (e.g. RNA editing, trans-splicing), (iii) its assembly follows unique routes, (iv) it includes an additional functional domain which contains carbonic anhydrases and (v) it is, indirectly, involved in photosynthesis. Comprising about 50 distinct protein subunits, complex I of plants is very large. However, an even larger number of proteins are required to synthesize these subunits and assemble the enzyme complex. This review aims to follow the complete "life cycle" of plant complex I from various molecular perspectives. We provide arguments that complex I represents an ideal model system for studying the interplay of respiration and photosynthesis, the cooperation of mitochondria and the nucleus during organelle biogenesis and the evolution of the mitochondrial oxidative phosphorylation system.

Organisationseinheit(en)

Institut für Pflanzengenetik
Abteilung Pflanzenmolekularbiologie und Pflanzenproteomik

Externe Organisation(en)

Universität Ulm
Max-Planck-Institut für molekulare Pflanzenphysiologie
Ludwig-Maximilians-Universität München (LMU)
Humboldt-Universität zu Berlin (HU Berlin)
Rheinische Friedrich-Wilhelms-Universität Bonn

Typ

Artikel

Journal

MITOCHONDRION

Band

19

Seiten

295-313

Anzahl der Seiten

19

ISSN

1567-7249

Publikationsdatum

21.02.2014

Publikationsstatus

Veröffentlicht

Peer-reviewed

Ja

ASJC Scopus Sachgebiete

Molekularmedizin, Molekularbiologie, Zellbiologie

Elektronische Version(en)

https://doi.org/10.15488/11656 (Zugang: Offen)
https://doi.org/10.1016/j.mito.2014.02.006 (Zugang: Geschlossen)